Authors‘ response
What is the means for identifying prompt-growing and you will slow-developing protein-programming genes? If the experience simply „Use Ka“, I’d believe people have complete you to definitely just before.
Authors‘ effect
You will find altered the label in order to „Nonsynonymous replacement rate (Ka) are a comparatively consistent factor to own identifying fast-evolving and slow-evolving proteins-programming family genes“. You will find appeared the newest relevant literature meticulously and possess maybe not located courses with over particularly comprehensive recommendations on the steps.
Sources
Lander Es, Linton LM, Birren B, Nusbaum C, Zody MC, Baldwin J, Devon K, Dewar K, Doyle Yards, FitzHugh W, mais aussi al: Initial sequencing and you may analysis of one’s peoples genome. Nature. 2001, 409: 860-921. 7062.
Demuth JP, De- Bie T, Stajich JE, Cristianini N, Hahn MW: Brand new progression regarding mammalian gene parents. PLoS That. 2006, 1: e85-/journal.pone.0000085.
Williamson SH, Hubisz MJ, Clark AG, Payseur BA, Bustamante Computer game, Nielsen Roentgen: Localizing present transformative development throughout the people genome. PLoS Genet. 2007, 3: e90-/diary.pgen.0030090.
Bustamante Cd, Fledel-Alon A beneficial, Williamson S, Nielsen Roentgen, Hubisz MT, Glanowski S, Tanenbaum DM, White TJ, Sninsky JJ, Hernandez RD, Civello D, Adams MD, Cargill Meters, Clark AG: Pure choice to the proteins-coding family genes in the person genome. Characteristics. 2005, 437: 1153-1157. /nature04240.
Nielsen Roentgen, Bustamante C, Clark AG, Glanowski S, Sackton TB, Hubisz MJ, Fledel-Alon An excellent, Tanenbaum DM, Civello D, White TJ, J Sninsky J, Adams MD, Cargill Yards: A scan getting definitely picked family genes on the genomes off humans and you can chimpanzees. PLoS Biol. 2005, 3: e170-/log.pbio.0030170.
Kosiol C, Vinar T, da Fonseca RR, Hubisz MJ, Bustamante Computer game, Nielsen Roentgen, Siepel A good: Activities out of positive solutions for the half dozen Mammalian genomes. PLoS Genet. 2008, 4: e1000144-/record.pgen.1000144.
Clark AG, Glanowski S, Nielsen R, Thomas PD, Kejariwal An excellent, Todd MA, Tanenbaum DM, Civello D, Lu F, Murphy B, Ferriera S, Wang Grams, Zheng X, White TJ, Sninsky JJ, Adams MD, Cargill M: Inferring nonneutral evolution off people-chimp-mouse orthologous gene trios. Science. 2003, 302: 1960-1963. /science.1088821.
Locke DP, Hillier LW, Warren Bathroom, Worley KC, Nazareth LV, Muzny DM, Yang SP, Wang Z, Chinwalla During the, Minx P, mais aussi al: Relative and you may market data from orang-utan genomes. Characteristics. 2011, 469: 529-533. /nature09687.
Gibbs RA, Rogers J, Katze Milligrams, Bumgarner R, Weinstock GM, Mardis Emergency room, Remington KA, Strausberg RL, Venter JC, Wilson RK, et al: Evolutionary and biomedical understanding on rhesus macaque genome. Research. 2007, 316: 222-234. /science.1139247.
Wade CM, Giulotto E, Sigurdsson S, Zoli Yards, Gnerre S, Imsland F, Lear TL, Adelson DL, Bailey Age, Bellone RR, mais aussi al: Genome series, comparative studies, and you can society genetics of residential pony. Research. 2009, 326: 865-867. /technology.1178158.
Lindblad-Toh K, Go CM, Mikkelsen TS, Karlsson EK, Jaffe DB, Kamal M, Clamp M, Chang JL, Kulbokas EJ, Zody MC, et al: Genome series, relative analysis and haplotype structure of domestic dog. Characteristics. 2005, 438: 803-819. /nature04338.
Elsik CG, Tellam RL, Worley KC, Gibbs RA, Muzny DM, Weinstock GM, Adelson DL, Eichler EE, Elnitski L, Guigo Roentgen, ainsi que al: The fresh genome sequence away from taurine cattle: a window to help you ruminant biology and you can advancement https://datingranking.net/eharmony-vs-okcupid/. Technology. 2009, 324: 522-528. /science.1169588.
Waterston RH, Lindblad-Toh K, Birney E, Rogers J, Abril JF, Agarwal P, Agarwala R, Ainscough Roentgen, Alexandersson Yards, An enthusiastic P, mais aussi al: 1st sequencing and you may comparative studies of the mouse genome. Nature. 2002, 420: 520-562. /nature01262.
Gibbs RA, Weinstock GM, Metzker ML, Muzny DM, Sodergren EJ, Scherer S, Scott Grams, Steffen D, Worley KC, Burch PE, mais aussi al: Genome sequence of one’s Brown Norway rat returns knowledge towards mammalian evolution. Nature. 2004, 428: 493-521. /nature02426.
Mikkelsen TS, Wakefield MJ, Aken B, Amemiya CT, Chang JL, Duke S, Garber Yards, Gentles AJ, Goodstadt L, Heger A, mais aussi al: Genome of your marsupial Monodelphis domestica reveals inside, 447: 167-177. /nature05805.
